The blade designed and manufactured by GE subsidiary LM Wind Power will "undergo a series of fatigue tests" to ensure the structure's durability.
It will be put through its paces at the Massachusetts Clean Energy Centre in Boston.
"Offshore wind represents an important energy source as the Commonwealth works to meet ambitious greenhouse gas reduction targets, and we look forward to working with the industry to drive down costs, improve efficiency and develop of a hub of activity here in Massachusetts," said Massachusetts governor Charlie Baker.
A first Haliade-X blade was shipped to the UK and the ORE Catapult testing facility in Blyth in early August 2019.
The first complete Haliade-X turbine has been installed onshore at the Port of Rotterdam for other tests.
It is the preferred turbine for the 3.6GW Dogger Bank offshore projects in the UK, and Ørsted's 1.1GW Ocean Wind and 120MW Skipjack sites in the US.