The firm said the move into the Mexican market, which will also serve North and South America, is a sign of confience in the region's market.
More than 1GW worth of blades will be able to be produced at the site in Matamoros, in north-east Mexico, on the border with the US.
"With the plant in Matamoros, we are responding to the sharp rise in global demand for our products.
"In addition to the existing rotor blade production facilities in different regions, we can now also manufacture our rotor blades in the vicinity of the North and Latin American growth markets. This increases significantly our competitiveness," said José Luis Blanco, CEO of Nordex.
Work on the new facility is underway, with the installations of production moulds currently taking place. The site is due to begin operations in spring 2019 and will create 900 jobs.
US-based blade supplier TPI Composites also produces blades for Vestas in Matamoros.