The job reductions in the US are part of SGRE's global strategy to rationalise its manufacturing facilities following the merger of Siemens' wind business with Gamesa in 2017.
SGRE now employs approximately 1,900 people in the US across its onshore, offshore and servicing divisions.
Deliveries of the new SG-2.7-129 turbine, designed in the US, will start at early in 2019, said Miranda.
The nacelle will be produced at SGRE's Hutchinson plant in Kansas, and the blades at the Fort Madison plant in Iowa.
Miranda said SGRE has invested $30 million in updating the two plants.
SGRE is the third largest OEM in terms of sales in the US, behind Vestas and GE.
Asked how the company will weather a smaller US market after the phase-out of the Production Tax Credit (PTC), Miranda said: "It's true that the pie will be smaller. But our 4X series will be the best in class. It will allow us to be very competitive in the US."
SGRE's 4.2-125 turbine was unveiled late in 2017.
The American Wind Energy Association (AWEA) will hold its Windpower 2018 conference and exhibition in Chicago (7-10 May). Windpower Monthly will bring all of the coverage from the show across the week.